model based prediction of plateau pressure in mechanically ventilated patients

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ID: 192351
2017
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Abstract
The risk of ventilator induced lung injury in mechanically ventilated (MV) critically ill patients can be mitigated by patient-specific optimisation of ventilator settings. Recent studies have shown that driving pressure, i.e. the difference between plateau pressure (Pplat) and PEEP, is a strong indicator for survival in MV patients suffering from ARDS. However, to measure Pplat, an extended end-inspiratory pause (EIP) has to be applied, possibly interrupting ventilation therapy. This study presents a method for predicting Pplat from normal breaths in MV patients.
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Authors ;Kretschmer Jörn;Patel Aakash;Docherty Paul D.;Laufer Bernhard;Möller Knut
Journal materials science and engineering c
Year 2017
DOI
10.1515/cdbme-2017-0062
URL
http://www.degruyter.com/view/j/cdbme.2017.3.issue-2/cdbme-2017-0062/cdbme-2017-0062.xml?format=INT
Keywords
mathematical model decision support mechanical ventilation

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