oral anticoagulation to reduce risk of stroke in patients with atrial fibrillation: current and future therapies

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ID: 191548
2013
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Abstract
Alpesh AminHospitalist Program, University of California, Irvine, Orange, CA, USAAbstract: Atrial fibrillation (AF) is associated with an increased incidence and severity of strokes. The burden of AF-related stroke is expected to increase in parallel with the aging of the population. Oral anticoagulation with warfarin has been the pharmacologic standard for stroke risk reduction in patients with AF. When used with close attention to dosing and monitoring, warfarin is effective prophylactic therapy against thromboembolic stroke. However, it is underused by physicians, in part because of the known risks of adverse events with warfarin. Consequently, many patients with AF live with an avoidably elevated risk of stroke. New options, ie, oral anticoagulants with novel mechanisms of action, have recently been approved to reduce the risk of stroke in AF, and others are in development. These newer agents may address some of the complexities of warfarin use while providing similar or better efficacy and safety.Keywords: atrial fibrillation, stroke, oral anticoagulants
Reference Key
a2013clinicaloral Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Amin A
Journal imaging science journal
Year 2013
DOI
DOI not found
URL
https://www.dovepress.com/oral-anticoagulation-to-reduce-risk-of-stroke-in-patients-with-atrial--peer-reviewed-article-CIA
Keywords
Atrial fibrillation stroke

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