hyperzincaemia in a pet african giant rat (cricetomys gambianus waterhouse, 1840) : clinical communication

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ID: 190846
2007
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Abstract
Presented is an African giant rat (Cricetomys gambianus) following zinc ingestion. The sick rat was lethargic, withdrawn, had soft, mucus-impregnated faeces and diahorrea, foot twitching and icterus. Comparative age, sex and body weight (b.wt.)-matched analyses were made with a healthy giant rat. Twelve-hourly Urine volume (UV), Haematocrit (Hct), urinary glucose, plasma zinc and Alkaline Phosphatase (ALP) were performed over an 8-week period. Full blood counts were performed and differential WBC counts and microscopic observations were made on blood smears obtained from both healthy and sick rats. Consecutive blood samples were drawn at the end of each week (Weeks <2-6 treatment; Weeks 7-8 post-treatment). Treatment involved oral vitamin B12 supplement at 4 µg / day and 2m diethylenetriaminepentaacetic acid (DTPA) intramuscular injections at 1m / 450g b.wt. / 5 wks (Week 2 - 6). Day 1 showed neutropaenia, Heinz bodies on RBCs (reticulocytes and immature forms). Zinc (Day 1 - end Week 7), glucose (Day 1 - end Week 4), ALP (Day 1 - Week 4) and UV were elevated (Day 1 - end Week 6). Indications of moderate zinc toxicosis following ingestion and stress-associated glucosuria were concluded.
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cooper2007journalhyperzincaemia Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;R.G. Cooper;K.H. Erlwanger
Journal race: revista de administração, contabilidade e economia
Year 2007
DOI
10.4102/jsava.v78i3.310
URL
https://jsava.co.za/index.php/jsava/article/view/310
Keywords Keywords not found

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