efeito sedativo da romifidina em muares (equus asinus caballus) não domados sedative effect of romifidine in unmated mules (equus asinus caballus)

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ID: 190463
1999
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Abstract
Com o objetivo de verificar a viabilidade do uso da romifidina em muares e avaliar seus efeitos sedativos na espécie, utilizou-se essa droga para contenção farmacológica de burros não domados, submetidos à orquiectomia bilateral. Em uma primeira etapa, visando a verificar sua viabilidade, a romifidina foi aplicada por via intravenosa em oito animais nas doses de 0,04 e 0,08mg/kg. Já na Segunda etapa, compararam-se seus efeitos sedativos após a aplicação, por via intramuscular, das doses de 0,04, 0,08 e 0,12mg/kg, em três grupos de sete animais. Os sinais da sedação induzida pela romifidina foram semelhantes aos já descritos para eqüinos, porém, verificou-se menor intensidade, dentro das doses utilizadas. Apesar da via intravenosa ter produzido efeitos mais intensos, a via intramuscular foi a da escolha devido à facilidade e à segurança da aplicação, sendo a dose de 0,12mg/kg a que produziu melhores resultados. A romifidina foi considerada como uma opção viável para contenção de muares não domados.
With the intetion to study the viability of the use and the sedative effects of the romifidine in mules, this drug was used for chemical restraint in untamed burros, that were subjected to bilateral orquiectomy. In a first fase, the viability was investigated in eight animals that were injected intravenously with 0.04 and 0.08mg/kg. In a second fase, the sedative effects were compared in three groups of seven animals that were injected with intramuscular doses of 0.04, 0.08 and 0.12mg/kg. The sedative signs of romifidine in mules were similar with that had been described for equine, however lower intensity were seen with same doses. Indeed the intravenous route produced effects more intense, the facility and safety made the intramuscular route better. By this route the 0.12mg/kg dose was the most efficient. The romifidine provided sedation which might be clinically useful in untamed mules.
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Authors ;Geraldo Eleno Silveira Alves;Rafael Resende Faleiros;Valentim Arabicano Gheller;Mauro Machado Vieira
Journal Trials
Year 1999
DOI
10.1590/S0103-84781999000100010
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84781999000100010
Keywords
anaesthesia anesthesia

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