bioindicators in radiation protection

Clicks: 203
ID: 189067
2008
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Abstract
Biodosimetry is the evaluation of absorbed dose using bioindicators. Among chromosomal aberrations, scoring of dicentrics from peripheral human blood has been used as gold standard for biodosimetry, although in case of large scale incidents its use presents some drawbacks. Advances in technology have led to new investigations allowing or permitting the use of new methods which not only improve this "classical" biodosimetry but permits the design of other bioindicators making possible faster analyses, particularly in events where many persons may have been exposed. This report presents an overview of some recent studies developed by the "Grupo de Estudos em Radioproteção e Radioecologia - GERAR", Nuclear Energy Department of UFPE - Brazil, involving biodosimetry.
Biodosimetria pode ser definida como a avaliação da dose absorvida individualmente usando bioindicadores. Entre as aberrações cromossômicas, a quantificação de discêntricos em sangue periférico humano tem sido usada como padrão ouro in biodosimetria, embora essa técnica possua várias limitações em casos de incidentes envolvendo um grande número de indivíduos. Os avanços tecnológicos têm proporcionado novas ferramentas de investigações, resultando no desenvolvimento de novos métodos com intuito de otimizar essa dosimetria biológica "clássica", bem como na descoberta de novos bioindicadores, com o objetivo de possibilitar avaliação de exposição individual de forma mais rápida, em particular em situações envolvendo grande número de indivíduos expostos. Este texto apresenta um breve relato de alguns dos estudos desenvolvidos pelo Grupo de Estudos em Radioproteção e Radioecologia - GERAR, do Departamento de Energia Nuclear da UFPE - Brasil, associados ao emprego dos "clássicos" e novos bioindicadores em biodosimetria.
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amaral2008brazilianbioindicators Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Ademir Amaral;Thiago Salazar Fernandes;Mariana Brayner Cavalcanti
Journal current drug delivery
Year 2008
DOI
10.1590/S1516-89132008000700015
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700015
Keywords
bioindicators

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