second hit in cervical carcinogenesis process: involvement of wnt/beta catenin pathway
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Abstract
Abstract
The Human papillomavirus plays an important role in the initiation and progression of cervical cancer. However, it is a necessary but not sufficient cause to develop invasive carcinoma; hence, other factors are required in the pathogenesis of this malignancy. In this review we explore the hypothesis of the deregulation of wnt/β-catenin signaling pathway as a "second hit" required to develop cervical cancer.
| Reference Key |
carlos2008internationalsecond
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| Authors | ;Perez-Plasencia Carlos;Duenas-Gonzalez Alfonso;Alatorre-Tavera Brenda |
| Journal | journal of central south university of technology (english edition) |
| Year | 2008 |
| DOI |
10.1186/1755-7682-1-10
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