the effects of antidepressants on gastric ulcer

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ID: 188507
2013
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Abstract
In their daily practice, psychiatrists often experience gastriccomplaints in patients beside psychiatric disorders.Peptic ulcer is one of the diseases, which accompanyto psychiatric disorders including mainly depression. Itis shown that antidepressants can inflame the bleedingsincluding gastrointestinal (GI) bleedings, while they havepositive effect on ulcer healing. In this review, studies,which conducted about the positive or negative effects ofantidepressant drugs on ulcer treatment were examined.Accordingly; it was found that opipramol, amitriptyline,imipramine that of tricyclic antidepressants was found tobe helpful in healing of the ulcer. It was stated that SelectiveSerotonin Reuptake Inhibitors generally inflamedulcers, exceptionally fluvoxamine and fluoxetine reducedulcer; moclobemide that of monoamine-oxidase inhibitorand tianeptine and mirtazapine that of atypical antidepressantshad positive effect in ulcer healing. To be carefulin choosing the appropriate antidepressant in psychiatricpatients with gastric ulcer is important in the prognosisof both ulcer and depression.Key words: peptic ulcer; depression; antidepressant drugs
Reference Key
gne2013diclethe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Mehmet Latif Güneş;Esra Yazici;Ahmet Bülent Yazıcı;Irmak Ferah;Elif Çadırcı
Journal journal of sulfur chemistry
Year 2013
DOI
10.5798/diclemedj.0921.2013.04.0362
URL
http://www.diclemedj.org/upload/sayi/29/Dicle%20Med%20J-01809.pdf
Keywords
depression antidepressant drugsmedicinemedicine (general)

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