shape transitions in anisotropic multicomponent lipid tubules
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ID: 188057
2016
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Abstract
Abstract Ternary mixtures of saturated and unsaturated lipids together with cholesterol can be induced to phase separate by photo-peroxidation into lipid-ordered Lo and lipid-disordered Ld domains. Because these have different mechanical properties, the phase separation is accompanied by dramatic changes in morphology. This work considers a tubule composed of Ld phase with Lo phase inclusions that possess greater rigidity; this system has been shown experimentally by Yuan and coworkers to spontaneously adopt either banded or disc configurations following phase separation. The static behaviour of inter-domain interactions is analyzed in each of these geometries by solving the linearized shape equations. These calculations suggest a possible mechanism by which the two structures form.
| Reference Key |
eatherton2016frontiersshape
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|---|---|
| Authors | ;Tim eAtherton |
| Journal | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases |
| Year | 2016 |
| DOI |
10.3389/fmats.2016.00026
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| URL | |
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