effect of topical combination of flaxseed oil and alcoholic extract of ceylon cinnamon in full-thickness surgical wound healing in a rabbit model

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ID: 187915
2014
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Abstract
The aim of the current study was to evaluate of wound healing activity of flaxseed oil and its combination with Cinnamon hydroalcoholic extract on excision of wound healing model in rabbit. Sixty New Zealand white rabbits were randomly allocated into 4 experimental groups. Two full-thickness skin excisional wounds were created on thoracolumbar region on each side of the dorsal midline in each rabbit. Rabbits in group 1 did not receive any treatments. In group 2, rabbits received placebo ointment; in group 3, animals were treated with flaxseed oil 2% ointment. In group 4, rabbits received ointment containing a combination of flaxseed 2%+Cinnamon hydroalcoholic extract 3%. Wound area (mm2) was determined on days 4, 8, 12, 16 and 20 using a transparent paper. Tissue samples were collected on days 3, 7, 14 and 20 for histopathological studies with Masson trichrome staining. According to the results, ointment containing a combination of flaxseed oil 2%+Cinnamon hydroalcoholic extract 3% significantly decreased wound area on all days after wounding in comporison with the control (p
Reference Key
farahpour2014sb/shins-ieffect Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;mohammadreza Farahpour;majid ghafouri
Journal international journal of pediatrics
Year 2014
DOI
DOI not found
URL
http://jvcp.iaut.ac.ir/article_517157_0321eb6ad472604fb5d082359db25b91.pdf
Keywords
wound healing flaxseed oil rabbitveterinary medicine excision wound

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