the brain decade in debate: ii. panic or anxiety? from animal models to a neurobiological basis

Clicks: 292
ID: 186214
2001
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Abstract
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification.
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andreatini2001brazilianthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;R. Andreatini;C. Blanchard;R. Blanchard;M.L. Brandão;A.P. Carobrez;G. Griebel;F.S. Guimarães;S.L. Handley;F. Jenck;J.R. Leite;J. Rodgers;L.C. Schenberg;C. Da Cunha;F.G. Graeff
Journal Free radical biology & medicine
Year 2001
DOI
10.1590/S0100-879X2001000200001
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200001
Keywords
anxiety 5-ht fear amygdala serotonin benzodiazepines

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