normal pressure hydrocephalus, a possible complication in igg4-related disease

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ID: 185456
2016
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Abstract
We report a 75-year-old man with glucocorticoid-responsive normal pressure hydrocephalus (NPH) complicated with tubulointerstitial renal disease, protein-losing gastroenteropathy (PLG) and elevated serum IgG4, which might be a possible subset of IgG4-related disease (IgG4-RD). Although either PLG or NPH, especially in combination, has rarely been reported in IgG4-RD, the glucocorticoid-responsive nature of every abnormality observed in the patient supports the diagnosis of IgG4-RD. Of course, pathological confirmation is essential to fulfill the recently raised diagnostic criteria, however, such invasive procedure might not always be indicated in high-risk patients. Our report illustrates that IgG4-RD might be considered as one of the underlying causes and/or the aggravating factors of NPH before shunt operation.
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kobayashi2016interdisciplinarynormal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Hiroshi Kobayashi, Masaaki Uehara, Aya Oda, Erika Matsubara, Hiroyuki Baba, Ryo Matsumiya, Noritada Yoshikawa, Osamu Hosono, Hirotoshi Tanaka
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Journal advances in materials science and engineering
Year 2016
DOI
10.1016/j.inat.2016.03.009
URL
http://www.sciencedirect.com/science/article/pii/S2214751916300093
Keywords
normal pressure hydrocephalus igg4-related disease diseases of the nervous system

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