normal pressure hydrocephalus, a possible complication in igg4-related disease

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ID: 185456
2016
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Abstract
We report a 75-year-old man with glucocorticoid-responsive normal pressure hydrocephalus (NPH) complicated with tubulointerstitial renal disease, protein-losing gastroenteropathy (PLG) and elevated serum IgG4, which might be a possible subset of IgG4-related disease (IgG4-RD). Although either PLG or NPH, especially in combination, has rarely been reported in IgG4-RD, the glucocorticoid-responsive nature of every abnormality observed in the patient supports the diagnosis of IgG4-RD. Of course, pathological confirmation is essential to fulfill the recently raised diagnostic criteria, however, such invasive procedure might not always be indicated in high-risk patients. Our report illustrates that IgG4-RD might be considered as one of the underlying causes and/or the aggravating factors of NPH before shunt operation.
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kobayashi2016interdisciplinarynormal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Hiroshi Kobayashi;Masaaki Uehara;Aya Oda;Erika Matsubara;Hiroyuki Baba;Ryo Matsumiya;Noritada Yoshikawa;Osamu Hosono;Hirotoshi Tanaka
Journal advances in materials science and engineering
Year 2016
DOI
10.1016/j.inat.2016.03.009
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