production of chemically modified chitosan microspheres by a spraying and coagulation method

Clicks: 206
ID: 184862
2007
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Abstract
Chitosan microspheres can be used in several applications, as biomaterials, in biotechnology processes and as adsorbents. The control of particle size in microsphere production is important to make these applications viable. This study focuses on the production and morphological characterization of chitosan microspheres. Microspheres were prepared by a spraying and coagulation process. Particles underwent chemical modifications with glutaraldehyde, epichlorohydrin or acetic anhydride treatments. The microspheres presented a fairly good sphericity (0.74) but an irregular micro-surface morphology. The mean particle size (MPS) ranged from 140 to 281 mum and the mean standard deviation (MSD) from 119 to 238 mm. The conditions were modelled to provide desired MPS and MSD by using the response surface methodology (RSM).
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Authors ;Marco Antonio Torres;Rodrigo Silveira Vieira;Marisa Masumi Beppu;Eduardo José Arruda;Cesar Costapinto Santana
Journal Majalah Ilmiah Teknologi Elektro
Year 2007
DOI
10.1590/S1516-14392007000400005
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392007000400005
Keywords
chitosan mechanics of materials

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