mohs micrographic surgery for dermatofibrosarcoma protuberans of the vulva

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ID: 183905
2009
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Abstract
Introduction. Dermatofibrosarcoma Protuberans (DFSP) is a rare cutaneous tumour of low/intermediate malignant potential, which occasionally arises on the vulva. Historically, the treatment has been wide local excision (WLE). Mohs micrographic surgery (MMS) is now recommended to ensure precise margin control. MMS to treat DFSP of the trunk and extremities is well documented. However, no report to date has described its use in vulval DFSP. Case History. A 39 year old woman presented with a longstanding nodule in the left labium majus. Histology after surgical removal showed an incompletely excised DFSP. MMS was undertaken with primary closure of the defect. Three years following treatment there is no evidence of recurrence. Discussion. The local recurrence rate of DFSP after WLE ranges from 0–75%. Finger-like projections from DFSP into surrounding tissue often results in incomplete excision. Representative vertical sections used in WLE assess less than 1% of the total tumour margin. MMS uses systematic horizontal sectioning. 100% of the tumour margin is microscopically examined. MMS is now advocated to ensure precise margin control.
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doufekas2009obstetricsmohs Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;K. Doufekas;T. J. Duncan;K. M. Williamson;S. Varma;D. Nunns
Journal vìsnik nacìonalʹnogo avìacìjnogo unìversitetu
Year 2009
DOI
10.1155/2009/547672
URL
http://dx.doi.org/10.1155/2009/547672
Keywords
gynecology and obstetrics

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