alkaloids and triterpene from almeidea coerulea (nees and mart.) a. st.-hil. and anti-leishmanial activity

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ID: 183891
2011
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Abstract
The dichloromethane extract of Almeidea coerulea stems yielded the (11-hydroxyrutaecarpine alkaloid reported for the first time from this species) and the triterpene (28-hydroxy-28, 29-dihydrolupeol). The dictamine, skimianine, sitosterol and stigmasterol were also isolated from methanol extract. Extracellular forms of Leishmania amazonensis (promastigotes) was tested with dichloromethane extract and 28-hydroxy-28, 29-dihydrolupeol with showed anti-leishmanial activity above 0.1 mg/mL and 75µg/mL (inhibited 50% promastigote growth), respectively.
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cortez2011brazilianalkaloids Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lucia Elaine Ranieri Cortez, Izabel Cristina Piloto Ferreira, Valdrinez Campana Lonardoni, Antonio Gilberto Ferreira, Paulo Cesar Vieira, Maria Fátima das Graças Fernandes da Silva, João Batista Fernandes, Diógenes Aparicio Garcia Cortez
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Journal current drug delivery
Year 2011
DOI
10.1590/S1516-89132011000100008
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000100008
Keywords
rutaceae anti-leishmanial activitybiotechnology

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