seroprevalence of measles antibodies and predictors for seropositivity among chinese children

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ID: 183687
2017
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Abstract
Background: Supplementary measles immunization has been implemented since 2010 throughout China, yet few studies have reported its effect in the northwest regions. Methods: A cross-sectional study was conducted among children aged 2 to 4 years old (n = 755) from February to September 2014 in 25 towns of Qian County, Shaanxi Province. Blood samples were analyzed for measles antibodies using enzyme-linked immunosorbent immunoglobulin G (IgG) assays. Socio-demographic factors were assessed by questionnaire. Data on vaccine dose were collected from town medical records. Univariate and logistic regression analyses were used to determine factors associated with measles antibody seropositivity. Results: Measles antibody seroprevalence was 91.13% (95% CI: 89.52–92.83) in our sample. Compared with children whose mother’s highest education was primary school, seroprevalence was higher in children whose maternal education was middle school (adjusted OR: 1.4, 95% CI: 0.7–2.8), high school (adjusted OR: 2.4, 95% CI: 1.3–7.7), and college/university (adjusted OR: 2.9, 95% CI: 1.2–9.3). Vaccine dose was positively associated with seropositivity. Conclusions: Measles seroprevalence is high in China and is associated with the mother’s education and vaccine dose.
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wang2017internationalseroprevalence Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Xiaoqin Wang;Mei Ma;Zhaozhao Hui;Paul D. Terry;Yue Zhang;Rui Su;Mingxu Wang;Wei Gu;Ling Li
Journal archives of biochemistry and biophysics
Year 2017
DOI
10.3390/ijerph14060605
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