synthesis of mesoporous silica and modified as a drug delivery system of ibuprofen
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2016
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Abstract
In this work we synthesized of mesoporous silica nanoparticles and functionalized with 3-aminopropyltriethoxysilane to improve the loading and release of ibuprofen bonded to 3-aminopropyltriethoxysilane. sample were characterized by Fourier transform infrared spectroscopy, Scanning electron microscopy , X-ray diffraction, and ultraviolet-visible. the Fourier transform infrared spectroscopy result demonstrate that organic group were successfully functionalized onto mesoporous silica nanoparticles. Then, we investigate of the adsorption and release of ibuprofen as a drug delivery system in simulated body fluid. The result demonstrates that high adsorption capacity for drug with functionalized sample and slower drug release rate was achieved.
| Reference Key |
mortazavi2016journalsynthesis
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|---|---|
| Authors | ;Y. Mortazavi;S. M. Ghoreishi |
| Journal | process safety progress |
| Year | 2016 |
| DOI |
10.7508/jns.2016.01.014
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| URL | |
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