potential of epigenetic therapies in non-cancerous conditions

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ID: 181060
2014
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Abstract
There has been an explosion of knowledge in the epigenetics field in the past 20 years. The first epigenetic therapies have arrived in the clinic for cancer treatments. In contrast, much of the promise of epigenetic therapies for non-cancerous conditions remains in the laboratories. The current review will focus on the recent progress that has been made in understanding the pathogenic role of epigenetics in immune and inflammatory conditions, and how the knowledge may provide much needed new therapeutic targets for many autoimmune diseases. Dietary factors are increasingly recognized as potential modifiers of epigenetic marks that can influence health and diseases across generations. The current epigenomics revolution will almost certainly complement the explosion of personal genetics medicine to help guide treatment decisions and disease risk stratification.
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eyung2014frontierspotential Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Raymond eYung;Raymond eYung;Theresa eMau
Journal chemical record (new york, ny)
Year 2014
DOI
10.3389/fgene.2014.00438
URL
http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00438/full
Keywords
obesity diabetes mellitus diet genetics autoimmunity epigenetics therapies

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