possible drug–drug interaction in dogs and cats resulted from alteration in drug metabolism: a mini review

Clicks: 290
ID: 179850
2015
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Abstract
Pharmacokinetic drug–drug interactions (in particular at metabolism) may result in fatal adverse effects in some cases. This basic information, therefore, is needed for drug therapy even in veterinary medicine, as multidrug therapy is not rare in canines and felines. The aim of this review was focused on possible drug–drug interactions in dogs and cats. The interaction includes enzyme induction by phenobarbital, enzyme inhibition by ketoconazole and fluoroquinolones, and down-regulation of enzymes by dexamethasone. A final conclusion based upon the available literatures and author’s experience is given at the end of the review.
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sasaki2015journalpossible Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Kazuaki Sasaki;Minoru Shimoda
Journal reading & writing
Year 2015
DOI
10.1016/j.jare.2015.02.003
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