the effect of pulsed electromagnetic therapy on femoral bone micro-structure in ovariectomized rats

Clicks: 248
ID: 179414
2016
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #29 of 63 articles by views in bmc evolutionary biology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Background and Aim: Osteoporosis is a metabolic bone disease that can result from cytokines activity such as TNFɑ. The aim of this study was to evaluate the effect of pulsed electromagnet therapy on  femoral strength and bone microstructure in ovariectomized rats. Materials and Methods: In this experimental study, 30 rats were randomly divided into control, experimental1 (ovariectomized) and two experimental groups; namely ovariectomized and undergoing pulsed electromagnet groups.  The control and experimental1 groups were kept under controlled conditions, while the two experimental groups were treated with pulsed electromagnet (2.4 mT) from 12 postoperative weeks for 30min, 3days a week, for 10 weeks. Then, the subjects were sacrificed and their femoral bones were removed to determine the strength and the bone microstructure  parameters (the trabecular and cortical thicknesses and trabecular distances). In order to determine bone microstructures, the sections were prepared and stained with H&E. Then, Haworth method was used to measure. One-way ANOVA, repeated measurements, and Scheffe post- hoc tests were applied to analyze the obtained data. Statistical analyses were performed using SPSS software (version 16; Chicago,IL). Results: Despite equal initial weight of the subjects (P=0.15), they significantly gained weight after12 and also 22 postoperative weeks (P<,0.001). Cortical and trabecular thicknesses, and femoral strength respectively and significantly decreased in the experimental group 1 .X=220.80±5.90,P<0.001; X=90.34±5.73,P=0.001; X=5.15±1.07,P=0.002. In the experiment. group 2, decrease was .X=255.40±6.02,P<0.001; X=113.50±3.43, P=0.008; X=8.00±1.11,P=0.015; respectively, comparing with the control group (X=232.36±5.13, X=100.50±5.06, X=6.95±1.16). Cortical and trabecular thicknesses, and bone strength significantly increased in the experimental group 2, compared to the experimental  group 1(P<0.001).  There was also a significant decrease in the trabecular distance in the experimental group 2 (X=111.60±2.87) compared to the experimental 1 (X=127.40±4.74, P<0.001). Conclusion: Pulsed electromagnet, can be effective on the osteoporosis improvement.
Reference Key
hojjati2016journalthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Sarah Hojjati;Farhad Daryanoosh;Salman Vojdani;Farzad Nazem
Journal bmc evolutionary biology
Year 2016
DOI
DOI not found
URL
http://journal.bums.ac.ir/browse.php?a_code=A-10-1812-1&slc_lang=en&sid=1
Keywords
osteoporosis bone density medicinemedicine (general)

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.