3-(4-fluorophenyl)-<em>n</em>-[4-(4-furan-2-yl-1-oxo-2,3,7-triazaspiro[4.5]dec-3-en-2-yl)phenyl]propionamide hydrochloride

Tiklamalar: 193
ID: 179384
2012
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Ozet
A simple and novel route for the synthesis of new spirocyclic propionamide derivative is developed. The present work involves <em>N</em>-arylation of pyrazolone (<strong>1</strong>) using copper(I) iodide catalyst followed by reduction to give amine (<strong>2</strong>). The coupling of <strong>2</strong> with 3-(4-fluorophenyl)propionic acid and deprotection of Boc group yields the title compound (<strong>3</strong>).
Referans Anahtari
narayana2012molbank3-(4-fluorophenyl)-&lt;em&gt;n&lt;/em&gt;-[4-(4-furan-2-yl-1-oxo-2,3,7-triazaspiro[4.5]dec-3-en-2-yl)phenyl]propionamide Kullanarak makale yazarken otomatik alinti icin bu anahtari kullanin SciMatic Makale Yoneticisi veya Tez Yoneticisi
Yazarlar ;Badiadka Narayana;Balladka Kunhanna Sarojini;Seranthimata Samshuddin;Rajagopalan Srinivasan
Dergi journal of chemical sciences
Yil 2012
DOI
10.3390/M771
URL
http://www.mdpi.com/1422-8599/2012/3/M771
Anahtar Kelimeler
reduction pyrazolone

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