semaphorin 3a, a potential target for low back pain.

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ID: 178197
2015
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Abstract
Low back pain is a common disorder. Pathological innervation and intervertebral disc degeneration are two major factors associated with this disease. Semaphorin 3A, originally known for its potent inhibiting effect on axonal outgrowth, is recently found to correlate with disease activity and histological features in some skeletal disorders. Based on its effects on innervation and vascularization, as well as enzyme secretion, we presume that semaphorin 3A may act as a potential target for low back pain.
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Authors ;Pengbin eYin;Houchen eLv;Lihai eZhang;Licheng eZhang;Peifu eTang
Journal Frontiers in chemistry
Year 2015
DOI
10.3389/fnagi.2015.00216
URL
http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00216/full
Keywords
low back pain neurosciences neuropsychiatry biological psychiatry neuropilins

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