synaptic e-i balance underlies efficient neural coding

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ID: 177142
2018
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Abstract
Both theoretical and experimental evidence indicate that synaptic excitation and inhibition in the cerebral cortex are well-balanced during the resting state and sensory processing. Here, we briefly summarize the evidence for how neural circuits are adjusted to achieve this balance. Then, we discuss how such excitatory and inhibitory balance shapes stimulus representation and information propagation, two basic functions of neural coding. We also point out the benefit of adopting such a balance during neural coding. We conclude that excitatory and inhibitory balance may be a fundamental mechanism underlying efficient coding.
Reference Key
zhou2018frontierssynaptic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Shanglin Zhou;Yuguo Yu
Journal Journal of enzyme inhibition and medicinal chemistry
Year 2018
DOI
10.3389/fnins.2018.00046
URL
http://journal.frontiersin.org/article/10.3389/fnins.2018.00046/full
Keywords
neuropsychiatry biological psychiatry

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