synthesis of novel tetrahydroquinoline derivatives from α,α′-bis(substituted-benzylidene)cycloalkanones
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ID: 177129
2016
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Abstract
In this paper, we describe a two-step synthesis of a series of substituted tetrahydroquinoline analogies. In the first step α,α′-bis(substituted-benzylidene)cycloalkanones are reacted with malononitrile to afford 2-amino-3-cyano-4H-pyrans. The second step involves the conversion of pyrans into 2-amino-5,6,7,8-tetrahydroquinoline-3-carbonitrile derivatives using NH4OAC.
| Reference Key |
sheikhhosseini2016journalsynthesis
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|---|---|
| Authors | ;Enayatollah Sheikhhosseini;Elinaz Farrokhi;Mohammad Ali Bigdeli |
| Journal | zaporožskij medicinskij Žurnal |
| Year | 2016 |
| DOI |
10.1016/j.jscs.2012.09.018
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| URL | |
| Keywords | Keywords not found |
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