rnai and antiviral defense in the honey bee

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ID: 177080
2015
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Ranked #120 of 150 articles by views in journal of photochemistry and photobiology b, biology

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Abstract
Honey bees play an important agricultural and ecological role as pollinators of numerous agricultural crops and other plant species. Therefore, investigating the factors associated with high annual losses of honey bee colonies in the US is an important and active area of research. Pathogen incidence and abundance correlate with Colony Collapse Disorder- (CCD-) affected colonies in the US and colony losses in the US and in some European countries. Honey bees are readily infected by single-stranded positive sense RNA viruses. Largely dependent on the host immune response, virus infections can either remain asymptomatic or result in deformities, paralysis, or death of adults or larvae. RNA interference (RNAi) is an important antiviral defense mechanism in insects, including honey bees. Herein, we review the role of RNAi in honey bee antiviral defense and highlight some parallels between insect and mammalian immune systems. A more thorough understanding of the role of pathogens on honey bee health and the immune mechanisms bees utilize to combat infectious agents may lead to the development of strategies that enhance honey bee health and result in the discovery of additional mechanisms of immunity in metazoans.
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brutscher2015journalrnai Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Laura M. Brutscher;Michelle L. Flenniken
Journal journal of photochemistry and photobiology b, biology
Year 2015
DOI
10.1155/2015/941897
URL
http://dx.doi.org/10.1155/2015/941897
Keywords
immunologic diseases allergy

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