on-line adaptive radiation therapy: feasibility and clinical study

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ID: 177064
2010
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Abstract
The purpose of this paper is to evaluate the feasibility and clinical dosimetric benefit of an on-line, that is, with the patient in the treatment position, Adaptive Radiation Therapy (ART) system for prostate cancer treatment based on daily cone-beam CT imaging and fast volumetric reoptimization of treatment plans. A fast intensity-modulated radiotherapy (IMRT) plan reoptimization algorithm is implemented and evaluated with clinical cases. The quality of these adapted plans is compared to the corresponding new plans generated by an experienced planner using a commercial treatment planning system and also evaluated by an in-house developed tool estimating achievable dose-volume histograms (DVHs) based on a database of existing treatment plans. In addition, a clinical implementation scheme for ART is designed and evaluated using clinical cases for its dosimetric qualities and efficiency.
Reference Key
li2010journalon-line Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Taoran Li;Xiaofeng Zhu;Danthai Thongphiew;W. Robert Lee;Zeljko Vujaskovic;Qiuwen Wu;Fang-Fang Yin;Q. Jackie Wu
Journal joule
Year 2010
DOI
10.1155/2010/407236
URL
http://dx.doi.org/10.1155/2010/407236
Keywords
neoplasms Oncology including cancer and carcinogens tumors

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