bioactive eunicellin-based diterpenoids from the soft coral cladiella krempfi
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ID: 173306
2011
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Abstract
Four new eunicellin-based diterpenoids, krempfielins A–D (1–4), along with two known compounds (5 and 6) have been isolated from a soft coral Cladiella krempfi. The structures of the new metabolites were elucidated by extensive spectroscopic analysis and by comparison with spectroscopic data of related known compounds. Compounds 5 and 6 were shown to exhibit cytotoxicity against a limited panel of cancer cell lines. Furthermore, compounds 2, 3, 5 and 6 were shown to exert significant in vitro anti-inflammatory activity against LPS-stimulated RAW264.7 macrophage cells.
| Reference Key |
dai2011marinebioactive
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|---|---|
| Authors | ;Chang-Feng Dai;Jyh-Horng Sheu;Ming-Shyan Huang;Zhi-Hong Wen;Chi-Jen Tai;Jui-Hsin Su |
| Journal | jixie gongcheng xuebao/journal of mechanical engineering |
| Year | 2011 |
| DOI |
10.3390/md9102036
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| URL | |
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