smqnr variants in clinical isolates of stenotrophomonas maltophilia in brazil
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ID: 173095
2013
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Abstract
SUMMARY Stenotrophomonas maltophilia contains a novel chromosomally-encoded qnr gene named Smqnr that contributes to low intrinsic resistance to quinolone. We described Smqnr in 13 clinical isolates of S. maltophilia from two Brazilian hospitals, over a 2-year period. The strains were identified by API 20 NE (bioMérieux, France). Susceptibility by microdilution method to trimetroprim/sulfamethoxazole, ciprofloxacin, levofloxacin, minocycline, ceftazidime, chloramphenicol and ticarcillin/clavulanate was performed according to CLSI. PCR detection of Smqnr gene was carried out. The sequence of Smqnr was compared with those deposited in GenBank. Pulsed-field gel electrophoresis (PFGE) of all strains was performed. Thirteen Smqnr positives isolates were sequenced and three novel variants of Smqnr were identified. All 13 Smqnr isolates had distinguishable patterns by PFGE. This is the first report of Smqnr in S. maltophilia isolated in Brazil.
| Reference Key |
gracia-paez2013revistasmqnr
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| Authors | ;Jorge Isaac Gracia-Paez;Juliana Rosa Ferraz;Ivan Avelino Franca E Silva;Flavia Rossi;Anna Sara Levin;Silvia Figueiredo Costa |
| Journal | 2017 12th international conference for internet technology and secured transactions, icitst 2017 |
| Year | 2013 |
| DOI |
10.1590/S0036-46652013000600008
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