the potential roles of t-type ca2+ channels in motor coordination
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ID: 173068
2013
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Abstract
Specific behavioral patterns are expressed by complex combinations of muscle coordination. Tremors are simple behavioral patterns and are the focus of studies investigating motor coordination mechanisms in the brain. T-type Ca2+ channels mediate intrinsic neuronal oscillations and rhythmic burst spiking, and facilitate the generation of tremor rhythms in motor circuits. Despite substantial evidence that T-type Ca2+ channels mediate pathological tremors, their roles in physiological motor coordination and behavior remain unknown. Here, we review recent progress in understanding the roles that T-type Ca2+ channels play under pathological conditions, and discuss the potential relevance of these channels in mediating physiological motor coordination.
| Reference Key |
epark2013frontiersthe
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|---|---|
| Authors | ;Young-Gyun ePark;Jeongjin eKim;Daesoo eKim;Daesoo eKim |
| Journal | Fish physiology and biochemistry |
| Year | 2013 |
| DOI |
10.3389/fncir.2013.00172
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| URL | |
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