penares sp sponge from menjangan island-water west bali national park: isolation of cytotoxic compounds

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ID: 172794
2017
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Abstract
Sponges are multicellular animals which have cytotoxic compounds. In this study, isolation and cytotoxic activity of Penares sp sponge from Menjangan island-water West Bali National Park have been carried out. The results showed that chloroform extract and GF V Penares sp fraction were toxic according to Brine Shrimp Lethality Test method (each 85% and 63.3% mortality at 25μg/mL concentration). The isolation result of GF V fraction was obtained a compound (Spot 4) that is active as cytotoxic agent against T47D cells (IC50 of 12.7 ug/mL). Spot 4 is a terpenoid compound which has conjugated double bonds.
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setyowati2017majalahpenares Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Erna Prawita Setyowati, Sudarsono Sudarsono, Retno Murwanti
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Journal clinical microbiology reviews
Year 2017
DOI
10.22146/mot.31547
URL
https://jurnal.ugm.ac.id/TradMedJ/article/view/31547
Keywords
cytotoxic agents sponge

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