Isolation, Structural Elucidation, and Anti-HIV Activity of Daphnane Diterpenoids from .

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ID: 171929
2020
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Abstract
Five new [daphneodorins D-H (, , and -)] and seven known daphnane diterpenoids (- and -) were isolated from . The structures of the new compounds were elucidated by extensive physicochemical and spectroscopic analysis. The isolated compounds were evaluated for their anti-HIV activity against HIV-1 infection of MT4 cells. Nine daphnane diterpenoid orthoesters (-) showed potent anti-HIV activity with EC values of 1.5-7.7 nM.
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otsuki2020isolationjournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Otsuki, Kouharu;Li, Wei;Miura, Kasumi;Asada, Yoshihisa;Huang, Li;Chen, Chin-Ho;Lee, Kuo-Hsiung;Koike, Kazuo;
Journal Journal of natural products
Year 2020
DOI
10.1021/acs.jnatprod.0c00540
URL
Keywords
structural elucidation mapk cytotoxic activity apiaceae ferula sinkiangensis k.m.shen sesquiterpene coumarin

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