Stimuli-Responsive Drug Release from Smart Polymers.

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ID: 17156
2019
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Abstract
Over the past 10 years, stimuli-responsive polymeric biomaterials have emerged as effective systems for the delivery of therapeutics. Persistent with ongoing efforts to minimize adverse effects, stimuli-responsive biomaterials are designed to release in response to either chemical, physical, or biological triggers. The stimuli-responsiveness of smart biomaterials may improve spatiotemporal specificity of release. The material design may be used to tailor smart polymers to release a drug when particular stimuli are present. Smart biomaterials may use internal or external stimuli as triggering mechanisms. Internal stimuli-responsive smart biomaterials include those that respond to specific enzymes or changes in microenvironment pH; external stimuli can consist of electromagnetic, light, or acoustic energy; with some smart biomaterials responding to multiple stimuli. This review looks at current and evolving stimuli-responsive polymeric biomaterials in their proposed applications.
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wells2019stimuliresponsivejournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Wells, Carlos M;Harris, Michael;Choi, Landon;Murali, Vishnu Priya;Guerra, Fernanda Delbuque;Jennings, J Amber;
Journal journal of functional biomaterials
Year 2019
DOI
E34
URL
Keywords
structural analysis bio-inspiration biomimetics architectural education fiber composites parametric design structures antioxidant radical scavenging activity thymus mastichina anti-proliferative activity aqueous decoction hydroethanolic extract phenolic profiling salvianolic acid a isomer salvianolic acid isomer b/e isomer polymorphism molecular evolution amphibian immunogenetics paralog

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