Thermally Induced Reversible Self-Assembly of Apoferritin-Block Copolymer Complexes.

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ID: 17152
2019
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Abstract
Protein cages are interesting building blocks for functional supramolecular assemblies. A multi-responsive system composed of apoferritin and thermo-responsive block copolymers complexed through electrostatic interactions is described here. The polymers are linear chains with cationic and thermo-responsive blocks, and both diblock and triblock copolymers are studied. The apoferritin can be reversibly assembled and disassembled in aqueous solutions by altering the temperature and electrolyte concentration of the solutions. The control over the conditions is straightforward and all the components can be recovered, offering a potential alternative for systems requiring chemical or genetic modification of proteins.
Reference Key
korpi2019thermallymacromolecular Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Korpi, Antti;Skumial, Piotr;Kostiainen, Mauri A;
Journal Macromolecular rapid communications
Year 2019
DOI
10.1002/marc.201900308
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