community- and healthcare-associated infections in critically ill patients: a multicenter cohort study

Clicks: 272
ID: 171245
2015
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #51 of 169 articles by views in israel journal of chemistry

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 169 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Objective: To compare the spectrum of infection, comorbidities, outcomes, and mortality of patients admitted to the intensive care unit (ICU) due to community-acquired or healthcare-associated severe sepsis. Methods: This prospective cohort study was conducted in three university medical centers in Lebanon from February 2005 to December 2006. Patients with severe sepsis were included and followed up until hospital discharge or death. Results: One hundred and twenty patients were included of whom 60% had community-acquired infections (CAI) and 40% had healthcare-associated infections (HAI). The most common infection in both groups was pneumonia. Hematologic malignancies were the only comorbidity more prevalent in HAI than in CAI (p = 0.047). Fungal infections and extended-spectrum beta-lactamase (ESBL) organisms were more frequent in HAI than in CAI (p = 0.04 and 0.029, respectively). APACHE and SOFA scores were high and did not differ between the two groups, nor did the proportion of septic shock, while mortality was significantly higher in the HAI patients than in the CAI patients (p = 0.004). On multivariate analysis for mortality, independent risk factors were the source of infection acquisition (p = 0.004), APACHE II score (p = 0.006), multidrug-resistant Pseudomonas infections (p = 0.043), and fungal infections (p = 0.006). Conclusions: Severe sepsis and septic shock had a high mortality rate, especially in the HAI group. Patients with risk factors for increased mortality should be monitored and aggressive treatment should be administered.
Reference Key
dabar2015internationalcommunity- Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;George Dabar;Carine Harmouche;Pascale Salameh;Bertrand L. Jaber;Ghassan Jamaleddine;Mirna Waked;Patricia Yazbeck
Journal israel journal of chemistry
Year 2015
DOI
10.1016/j.ijid.2015.05.024
URL
http://www.sciencedirect.com/science/article/pii/S1201971215001332
Keywords
comorbidities mortalityinfectious and parasitic diseases

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.