sedation in traumatic brain injury

Clicks: 154
ID: 170642
2012
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Abstract
Several different classes of sedative agents are used in the management of patients with traumatic brain injury (TBI). These agents are used at induction of anaesthesia, to maintain sedation, to reduce elevated intracranial pressure, to terminate seizure activity and facilitate ventilation. The intent of their use is to prevent secondary brain injury by facilitating and optimising ventilation, reducing cerebral metabolic rate and reducing intracranial pressure. There is limited evidence available as to the best choice of sedative agents in TBI, with each agent having specific advantages and disadvantages. This review discusses these agents and offers evidence-based guidance as to the appropriate context in which each agent may be used. Propofol, benzodiazepines, narcotics, barbiturates, etomidate, ketamine, and dexmedetomidine are reviewed and compared.
Reference Key
flower2012emergencysedation Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Oliver Flower;Simon Hellings
Journal balkanlarda türk dili ve edebiyatı araştırmaları
Year 2012
DOI
10.1155/2012/637171
URL
http://dx.doi.org/10.1155/2012/637171
Keywords
critical care first aid intensive care medical emergencies

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