(+)-kunstlerone, a new antioxidant neolignan from the leaves of beilschmiedia kunstleri gamble
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ID: 170412
2011
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Abstract
A new neolignan, 3,4-dimethoxy-3′,4′-methylenedioxy-2,9-epoxy-6,7-cyclo-1,8-neolign-11-en-5(5H)-one, which has been named (+)-kunstlerone (1), together with six known alkaloids: (+)-norboldine (2), (+)-N-methylisococlaurine (3), (+)-cassythicine (4), (+)-laurotetanine (5), (+)-boldine (6) and (-)-pallidine (7), were isolated from the leaves of Beilschmiedia kunstleri. The structures were established through various spectroscopic methods notably 1D- and 2D-NMR, UV, IR and LCMS-IT-TOF. (+)- Kunstlerone (1) showed a strong antioxidant activity, with an SC50 of 20.0 µg/mL.
| Reference Key |
litaudon2011molecules(+)-kunstlerone,
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| Authors | ;Marc Litaudon;Mat Ropi Mukhtar;Jamaludin Mohamad;Khalijah Awang;A Hamid A Hadi;Abbas Mollataghi |
| Journal | Journal of ethnopharmacology |
| Year | 2011 |
| DOI |
10.3390/molecules16086582
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