prenatally programmed hypertension: role of maternal diabetes

Clicks: 147
ID: 170098
2011
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Abstract
Epidemiological and experimental studies have led to the hypothesis of the fetal origin of adult diseases, suggesting that some adult diseases might be determined before birth by altered fetal development. Maternal diabetes subjects the fetus to an adverse environment that has been demonstrated to result in metabolic, cardiovascular and renal impairment in the offspring. The growing amount of obesity in young females in developed and some developing countries should contribute to increasing the incidence of diabetes among pregnant women. In this review, we discuss how renal and extrarenal mechanisms participate in the genesis of hypertension induced by a diabetic status during fetal development.
Reference Key
gomes2011brazilianprenatally Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;G.N. Gomes;F.Z. Gil
Journal Free radical biology & medicine
Year 2011
DOI
10.1590/S0100-879X2011000900011
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