nutritional interventions to augment resistance training-induced skeletal muscle hypertrophy

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ID: 170002
2015
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Abstract
Skeletal muscle mass is regulated by a balance between muscle protein synthesis (MPS) and muscle protein breakdown (MPB). In healthy humans, MPS is more sensitive (varying 4-5 times more than MPB) to changes in protein feeding and loading indicating that it is the primary locus determining gains in muscle mass. Performing resistance exercise (RE) followed by the consumption of protein results in an augmentation of MPS and, over time, can lead to muscle hypertrophy. The magnitude of the RE-induced increase in MPS (and potentially subsequent hypertrophy) is dictated by a variety of factors including: the dose of protein, source of protein, and possibly the distribution and timing of post-exercise protein ingestion. In addition, RE variables such as frequency of sessions, time under tension, volume, and training status play roles in regulating MPS. This review provides a brief overview of our current understanding of how RE and protein ingestion can influence gains in skeletal muscle mass in young, healthy individuals. It is the goal of this review to provide nutritional recommendations for optimal skeletal muscle adaptation. Specifically, we will focus on how the manipulation of protein intake during the recovery period following RE augments the adaptive response.
Reference Key
morton2015frontiersnutritional Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Robert W Morton;Chris eMcGlory;Stuart M Phillips
Journal Journal of clinical and experimental dentistry
Year 2015
DOI
10.3389/fphys.2015.00245
URL
http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00245/full
Keywords
strength leucine anabolism whey

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