transcranial sonography on parkinson′s disease and essential tremor

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ID: 169911
2013
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Ranked #26 of 133 articles by views in 2017 ieee international conference on communication, networks and satellite, comnetsat 2017 - proceedings

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Abstract
Background: The study on transcranial sonocraphy (TCS) as a diagnostic test for Parkinson′s disease (PD) has been neglected in some hospitals. The current study was conducted as the first study to investigate the utility of TCS for diagnosis of PD and its ability to distinguish PD from essential tremor (ET) in an Iranian population. Materials and Methods: TCS of substantia nigra (SN) was performed on 50 PD, 48 ET, and 50 healthy controls by two blinded investigators. Results: Bilateral SN margin over 0.20 cm 2 was found in 39 (90%) and 7 (15%) in PD and ET patients, respectively. Furthermore, 4 (8%) of healthy control displayed this particular echo feature as well (false positives). SN hyperechogenicity ≥0.20 cm 2 was considered as a cut-off point to detected PD. Accordingly, TCS proved 90% (95% confidence interval [CI]: 77.85-97.35) sensitive and 92% ( 95% CI: 80.75-97.73 ) specific for the detection of PD by visualizing the SN. Conclusion: SN hyperechogenicity ≥20 cm 2 is a specific feature of PD. Since, the symptoms of PD and ET might be overlapping; this method seems to be reliable to confirm PD diagnosis in doubtful clinical cases. Further studies in years to come are warranted to shed light on standardized data for Iranian to enhance the validity of TCS.
Reference Key
chitsaz2013journaltranscranial Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Ahmad Chitsaz;Noushin Mehrbod;Mohammad Saadatnia;Mahboobeh Fereidan-Esfahani;Mojtaba Akbari;Seyed-Hossein Abtahi
Journal 2017 ieee international conference on communication, networks and satellite, comnetsat 2017 - proceedings
Year 2013
DOI
DOI not found
URL
http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2013;volume=18;issue=13;spage=28;epage=31;aulast=Chitsaz
Keywords
essential tremor parkinson transcranial sonographymedicine

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