chlorogenic acid: recent advances on its dual role as a food additive and a nutraceutical against metabolic syndrome

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ID: 169835
2017
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Abstract
Chlorogenic acid (5-O-caffeoylquinic acid) is a phenolic compound from thehydroxycinnamic acid family. This polyphenol possesses many health-promoting properties, mostof them related to the treatment of metabolic syndrome, including anti-oxidant, anti-inflammatory,antilipidemic, antidiabetic, and antihypertensive activities. The first part of this review will discussthe role of chlorogenic acid as a nutraceutical for the prevention and treatment of metabolicsyndrome and associated disorders, including in vivo studies, clinical trials, and mechanisms ofaction. The second part of the review will be dealing with the role of chlorogenic acid as a foodadditive. Chlorogenic acid has shown antimicrobial activity against a wide range of organisms,including bacteria, yeasts, molds, viruses, and amoebas. These antimicrobial properties can beuseful for the food industry in its constant search for new and natural molecules for thepreservation of food products. In addition, chlorogenic acid has antioxidant activity, particularlyagainst lipid oxidation; protective properties against degradation of other bioactive compoundspresent in food, and prebiotic activity. The combination of these properties makes chlorogenic acidan excellent candidate for the formulation of dietary supplements and functional foods.
Reference Key
santana-glvez2017moleculeschlorogenic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Jesús Santana-Gálvez;Luis Cisneros-Zevallos;Daniel A. Jacobo-Velázquez
Journal Journal of ethnopharmacology
Year 2017
DOI
10.3390/molecules22030358
URL
http://www.mdpi.com/1420-3049/22/3/358
Keywords
antioxidant antibiotic metabolic syndrome chlorogenic acid prebioticorganic chemistry

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