slowing down: age-related neurobiological predictors of processing speed
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2011
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Abstract
Processing speed, or the rate at which tasks can be performed, is a robust predictor of age-relatedcognitive decline and an indicator of independence among older adults. This review examines evidence for neurobiological predictors of age-related changes in processing speed, which is guided in part by our source based morphometry findings that unique patterns of frontal and cerebellar gray matter predict age-related variation in processing speed. These results, together with the extant literature on morphological predictors of age-related changes in processing speed, suggest that specific neural systems undergo declines and as a result slow processing speed. Future studies of processing speed - dependent neural systems will be important for identifying the etiologies for processing speed change and the development of interventions that mitigate gradual age-related declines in cognitive functioning and enhance healthy cognitive aging.
| Reference Key |
eckert2011frontiersslowing
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| Authors | ;Mark A Eckert |
| Journal | Journal of enzyme inhibition and medicinal chemistry |
| Year | 2011 |
| DOI |
10.3389/fnins.2011.00025
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