muscle strength rather than muscle mass is associated with osteoporosis in older chinese adults
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2018
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Abstract
Assessment of the association of muscle strength and muscle mass with osteoporosis (OP) is of special interest as muscles are a potential target for interventions (i.e., strength training).
Methods: A cross-sectional descriptive study encompassing people aged ≥ 60 years (average age: 66.9 ± 6.2 years; men, n = 516; women, n = 652) in the Hangu area of Tianjin, China. The study populations were invited to participate in a comprehensive geriatric assessment. OS was identified by measuring the calcaneal using a quantitative ultrasound and a T score of less than –2.5. Muscle characteristics included grip strength and appendicular skeletal muscle mass (ASM).
Results: The prevalence of OS in this study was 61.6% (male 52.1%, female 69.1%). Grip strength was negatively related to OS and after adjusting for all other variables, higher grip strength was found to be associated with a lower OS risk (p = 0.023). ASM/height2 was not associated with OS (p = 0.205).
Conclusion: Based on our study, muscle strength rather than muscle mass is negatively associated with OS in older people; thus, we should pay more attention to muscle strength training in the early stage of the OS.
| Reference Key |
ma2018journalmuscle
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|---|---|
| Authors | ;Yixuan Ma;Liyuan Fu;Liye Jia;Peipei Han;Li Kang;Hairui Yu;XiaoYu Chen;Xing Yu;Lin Hou;Lu Wang;Wen Zhang;Kaijun Niu;Qi Guo |
| Journal | Bioorganic & medicinal chemistry letters |
| Year | 2018 |
| DOI |
10.1016/j.jfma.2017.03.004
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