role of some epigenetic factors in dna damage response pathway

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ID: 167023
2017
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Ranked #5 of 9 articles by views in 2018 2nd national and 1st international digital games research conference: trends, technologies, and applications, dgrc 2018

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Abstract
The current review gives a brief account of the DNA damage response pathway and involvement of various epigenetic mechanisms in DNA damage response pathway. The main focus is on histone modifications leading to structural alterations in chromatin since the compact chromatin structure poses a major limitation in the DNA repair process. Based on this hypothesis, our laboratory has also evaluated certain histone deacetylase inhibitors as potential radiomitigators and the same has been discussed in brief at the end of the review.
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tiwari2017aimsrole Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Mrinalini Tiwari;Suhel Parvez;Paban K Agrawala
Journal 2018 2nd national and 1st international digital games research conference: trends, technologies, and applications, dgrc 2018
Year 2017
DOI
10.3934/genet.2017.1.69
URL
http://www.aimspress.com/Genetics/article/1344/fulltext.html
Keywords
epigenetics histone acetylation dna damage response

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