the role of pparγ in helicobacter pylori infection and gastric carcinogenesis

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ID: 166160
2012
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Abstract
Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that is important in many physiological and pathological processes, such as lipid metabolism, insulin sensitivity, inflammation, cell proliferation, and carcinogenesis. Several studies have shown that PPARγ plays an important role in gastric mucosal injury due to Helicobacter pylori (H. pylori). As H. pylori infection is the main etiologic factor in chronic gastritis and gastric cancer, understanding of the potential roles of PPARγ in H. pylori infection may lead to the development of a therapeutic target. In this paper, the authors discuss the current knowledge on the role of PPARγ in H. pylori infection and its related gastric carcinogenesis.
Reference Key
lee2012pparthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Jong-Min Lee;Sung Soo Kim;Young-Seok Cho
Journal Life (Basel, Switzerland)
Year 2012
DOI
10.1155/2012/687570
URL
http://dx.doi.org/10.1155/2012/687570
Keywords
Biology (General)

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