coinfection with rickettsia helvetica and herpes simplex virus 2 in a young woman with meningoencephalitis

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ID: 165766
2011
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Abstract
Herpes virus type 2 DNA was detected by PCR in the cerebrospinal fluid in a young woman presenting with headache, stiff neck and pleocytosis, and serological findings consistent with reactivation. Since she was exposed to ticks, Lyme disease and tick-borne encephalitis were excluded. Further investigation in an ongoing project, using PCR and sequencing of the amplified products, showed the presence of Rickettsia helvetica in the cerebrospinal fluid. The bacteria were also isolated in Vero cell culture, and microimmunofluorescence confirmed the development of antibodies against Rickettsia spp. with predominance of IgM reactivity consistent with recent infection. She was treated with antibiotics and improved rapidly. The patient could easily have been judged to have isolated herpes meningitis. Because Sweden and other European countries are endemic areas for rickettsioses, the paper reaffirms the importance of investigating for the presence of rickettsial infections in endemic areas in cases of meningitis of uncertain aetiology.
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nilsson2011casecoinfection Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Kenneth Nilsson;Katarina Wallménius;Carl Påhlson
Journal international journal for parasitology
Year 2011
DOI
10.1155/2011/469194
URL
http://dx.doi.org/10.1155/2011/469194
Keywords
Infectious and parasitic diseases

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