Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

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ID: 16559
2018
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Abstract
In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart.
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huang2018datadata Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Huang, Chih-Yang;Kuo, Chia-Hua;Pai, Pei-Ying;Ho, Tsung-Jung;Lin, Yueh-Min;Chen, Ray-Jade;Tsai, Fuu-Jen;Padma, V. Vijaya;Kuo, Wei-Wen;Huang, Chih-Yang;
Journal Data in brief
Year 2018
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http://www.sciencedirect.com/science/article/pii/S2352340917306364
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