pregnancy and cardiomyopathy after anthracyclines in childhood

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ID: 164286
2018
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Ranked #22 of 29 articles by views in substance abuse treatment, prevention, and policy

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Abstract
With advances in cancer therapy, there has been a remarkable increase in survival in children diagnosed with malignancies. Many of these children are treated with anthracyclines which are well known to cause cardiotoxicity. As more childhood cancer survivors reach childbearing age, many will choose to become pregnant. At this time, the factors associated with development of cardiomyopathy after anthracycline treatment are not clearly identified. It is possible that cardiac stress could predispose to cardiac deterioration in a patient with reduced functional reserve from prior anthracycline exposure. Pregnancy is one form of cardiovascular stress. The cardiac outcomes of pregnancy in childhood cancer survivors must be considered. In view of limited data, guidelines for pregnancy planning, management, and monitoring after cardiotoxic cancer therapy have not been established. This review summarizes the limited data available on the topic of pregnancy after anthracyclines in childhood.
Reference Key
thompson2018frontierspregnancy Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Kara Annette Thompson
Journal substance abuse treatment, prevention, and policy
Year 2018
DOI
10.3389/fcvm.2018.00014
URL
http://journal.frontiersin.org/article/10.3389/fcvm.2018.00014/full
Keywords
childhood pregnancy cardiotoxicity anthracyclines

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