synthesis and evaluation of 3-cyano-4-imino-2-methylthio-4h-pyrido[1,2-a]pyrimidine derivatives as potent antioxidant agents
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ID: 163763
2016
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Abstract
The bis (methylthio) methylene malononitrile (1) on treatment with 2-amino pyridine (2) in N,N-dimethyl formamide (DMF) and anhydrous potassium carbonate, gives 3-cyano-4-imino-2-(methylthio)-4H-pyrido[1,2-a]pyrimidine (3). The latter were further reacted with selected N-, O- and C-nucleophiles such as aryl amines, hetryl amines, substituted phenols and compounds containing active methylene groups.
| Reference Key |
vartale2016arabiansynthesis
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|---|---|
| Authors | ;S.P. Vartale;N.K. Halikar;Y.D. Pawar;K.V. Tawde |
| Journal | Behavioural brain research |
| Year | 2016 |
| DOI |
10.1016/j.arabjc.2011.12.007
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| URL | |
| Keywords | Keywords not found |
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