comparison between first- and second-generation cryoballoon for paroxysmal atrial fibrillation ablation

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ID: 162090
2016
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Abstract
Introduction. Cryoballoon (CB) ablation has emerged as a novel treatment for pulmonary vein isolation (PVI) for patients with paroxysmal atrial fibrillation (PAF). The second-generation Arctic Front Advance (ADV) was redesigned with technical modifications aiming at procedural and outcome improvements. We aimed to compare the efficacy of the two different technologies over a long-term follow-up. Methods. A total of 120 patients with PAF were enrolled. Sixty patients underwent PVI using the first-generation CB and 60 patients with the ADV catheter. All patients were evaluated over a follow-up period of 2 years. Results. There were no significant differences between the two groups of patients. Procedures performed with the first-generation CB showed longer fluoroscopy time (36.3±16.8 versus 14.2±13.5 min, resp.; p=0.00016) and longer procedure times as well (153.1±32 versus 102±24.8 min, resp.; p=0.019). The overall long-term success was significantly different between the two groups (68.3 versus 86.7%, resp.; p=0.017). No differences were found in the lesion areas of left and right PV between the two groups (resp., p=0.61 and 0.57). There were no significant differences in procedural-related complications. Conclusion. The ADV catheter compared to the first-generation balloon allows obtaining a significantly higher success rate after a single PVI procedure during the long-term follow-up. Fluoroscopy and procedural times were significantly shortened using the ADV catheter.
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conti2016cardiologycomparison Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sergio Conti, Massimo Moltrasio, Gaetano Fassini, Fabrizio Tundo, Stefania Riva, Antonio Dello Russo, Michela Casella, Benedetta Majocchi, Vittoria Marino, Pasquale De Iuliis, Valentina Catto, Salvatore Pala, Claudio Tondo
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Journal acta crystallographica section c, structural chemistry
Year 2016
DOI
10.1155/2016/5106127
URL
http://dx.doi.org/10.1155/2016/5106127
Keywords
Diseases of the circulatory (Cardiovascular) system

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