a hypothesis: supplementation with mushroom-derived active compound modulates immunity and increases survival in response to influenza virus (h1n1) infection

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ID: 161507
2011
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Abstract
We hypothesize that the mushroom-derived active compound may be a potential strategy for increasing survival in response to influenza virus (H1N1) infection through the stimulation of host innate immune response. The validity of the hypothesis can be tested by immune response to influenza infection as seen through survival percentage, virus clearance, weight loss, natural killer cell cytotoxicity, Tumor Necrosis Factor-α (TNF-α) and Interferon-gamma (IFN-γ) levels, lytic efficiency in the spleens of mice and inducible nitric oxide synthase mRNA expressions in RAW 264.7 murine macrophage cells. The hypothesis may improve people's quality of life, reduce the medical cost of our healthcare system and eliminate people's fears of influenza outbreak.
Reference Key
chunchao2011evidence-baseda Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Han Chunchao;Jian-you Guo
Journal ACS applied materials & interfaces
Year 2011
DOI
10.1093/ecam/neq037
URL
http://dx.doi.org/10.1093/ecam/neq037
Keywords
Other systems of medicine

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