efficacy and adverse effects of intravenous lignocaine therapy in fibromyalgia syndrome

Clicks: 563
ID: 161164
2002
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Abstract

Abstract

Background

To investigate the effects of intravenous lignocaine infusions (IV lignocaine) in fibromyalgia.

Methods

Prospective study of the adverse effects of IV lignocaine in 106 patients with fibromyalgia; retrospective questionnaire study of the efficacy of IV lignocaine in 50 patients with fibromyalgia.

Results

Prospective study: Two major (pulmonary oedema and supraventricular tachycardia) and 42 minor side-effects were reported. None had long-term sequelae. The commonest was hypotension (17 cases). Retrospective study: Pain and a range of psychosocial measures (on single 11-point scales) improved significantly after treatment. There was no effect of the treatment on work status. The average duration of pain relief after the 6-day course of treatment was 11.5 ± 6.5 weeks.

Conclusions

Intravenous lignocaine appears to be both safe and of benefit in improving pain and quality of life for patients with fibromyalgia. This needs to be confirmed in prospective randomised controlled trials.

Reference Key
gj2002bmcefficacy Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Treharne GJ;Southall JL;Raphael JH;Kitas GD
Journal millenium
Year 2002
DOI
10.1186/1471-2474-3-21
URL
http://www.biomedcentral.com/1471-2474/3/21
Keywords
depression pain benefits adverse effects psychosocial fibromyalgia lidocaine intravenous

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